L-Methylfolate (15 mg) Plus Methyl B12 Capsules

L-Methylfolate (15 mg) Plus Methyl B12 Capsules

 (Rated 4.9/5 based on +1475 reviews)
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Key Ingredients

  • Folate
  • Vitamin B12
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Size / Suggested Use

  • Size: 60 Capsules - 60 Servings
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Product Details

L-Methylfolate is a bioactive form of folate (B9) that requires fewer metabolic conversion steps in the body. This can help support efficient absorption and utilization. Formulated with Methylcobalamin B12 to help maintain healthy homocysteine metabolism, support normal nerve function, and promote cardiovascular well-being by aiding natural nitric oxide pathways.*A high-quality supplement formulated to help support a positive mood, promote healthy energy levels, enhance mental clarity, and encourage restful sleep.*Our high-quality L-Methylfolate and Methyl B12 supplement is formulated based on clinical research to support healthy methylation. Each capsule provides 15 mg of L-Methylfolate (5-MTHF) plus 500 mcg of Methyl B12. L-Methylfolate is a biologically active form of folate that requires minimal conversion by the body. This formulation is designed to help support a healthy mood and brain function.**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Methylated Folate: A Nutrient Form Some People Prefer for Genetic Support*

Certain MTHFR gene variations may affect how the body processes synthetic folic acid. Methylated forms like 5-MTHF can offer a more direct form of folate support.Methylated vitamins provide folate in a body-ready form, supporting bioavailability and cellular use.*

How L-Methylfolate Works in the Body

  • Supports neurotransmitters like serotonin, dopamine .*

  • Supports red blood cells production and detox in the body.*

  • Helps your homocysteine levels stay in check which is vital for heart and brain health.*

    Reasons to Love Our L-Methylfolate

    Designed for Efficient Absorption*

    No Conversion Required - Body-Ready Form*

    Enhanced with B12*

    See how L-Methylfolate Helped Others!

      Body-Ready Nutrients in One Easy Dose

      Supports Mood & Cognition*

      Supports Healthy Methylation*

      Supports Heart Health*

      Supports Nerve Cognition*

      Results Over Time

      • 3-7 Days: Gradual Support*

        Some individuals may begin to notice support for mental clarity, mood balance, and energy. This is also when nutritional support for red blood cell formation and homocysteine metabolism may begin.*

      • Weeks 4-8: Noticeable Support*

        Neurotransmitter production for the ‘feel good’ hormones like serotonin & dopamine goes up which can help with an improvement in mood and a reduction in symptoms of anxiety.*

      • Month 3-6: Ongoing Support*

        Some individuals may notice more consistent energy levels and support for healthy eating patterns. Users have also shared feeling more in tune with their overall wellness goals and daily routines.*

        Hear From Our Experts

        "As a health researcher, I view L-Methylfolate as an essential nutrient for neurological, emotional, and metabolic balance—especially in individuals with genetic variants like MTHFR. Triquetra’s L-Methylfolate line stands out for its clinically relevant dosing, exceptional purity, and highly bioavailable formulas, with options tailored for both adults and children. It’s a science-backed choice for those seeking therapeutic efficacy and uncompromising quality."

        Adriano Zanardi da Silva, M.Sc., Ph.D

        Frequently Asked Questions

        What is L-Methylfolate and how is it different from folic acid?

        L-Methylfolate is the active form of folate that your body can use immediately. Folic acid needs to be converted—and some people can’t do that well because of genetic mutations like MTHFR.

        What is Methyl B12 and why is it paired with L-Methylfolate?

        Methyl B12 (aka Methylcobalamin) is a highly bioavailable form of B12 that works synergistically with L-Methylfolate to support brain health, energy, and mood.

        Is this product safe if I’m pregnant or breastfeeding?

        Check with your doctor first. L-Methylfolate is often recommended during pregnancy, but always confirm with your healthcare provider.

        Can this supplement interact with medications?

        It is possible L-Methylfolate may interact with certain medications. It is always best to check with a healthcare provider before starting any supplements.

        Are there any known side effects?

        Most people tolerate it well. If you feel like you are sensitive to higher doses, you can work your way up to the full dose over time.


        How do I take it — with food or without?

        It can be taken with or without food, but some people prefer it with a meal to avoid mild stomach discomfort.